Immunoglobulin gene repertoire diversification and selection in the stomach – from gastritis to gastric lymphomas

Immunoglobulin gene repertoire diversification and selection in the stomach – from gastritis to gastric lymphomas

Chronic gastritis is characterized by gastric mucosal inflammation due to autoimmune responses or infection, frequently with Helicobacter pylori. Gastritis with H. pylori background can cause gastric mucosa-associated lymphoid tissue lymphoma (MALT-L), which sometimes further transforms into diffuse...

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Bibliographic Details
Main Authors: Miri eMichaeli, Hilla eTabibian-Keissar, Ginette eSchiby, Gitit eShahaf, Yishai ePickman, Lena eHazanov, Kinneret eRosenblatt, Deborah K Dunn-Walters, Iris eBarshack, Ramit eMehr
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Immunology
Subjects:
Gastritis
DLBCL
H. pylori
somatic hypermutation
B-cells
repertoire
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00264/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00264/full

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