PhTX-II a Basic Myotoxic Phospholipase A2 from Porthidium hyoprora Snake Venom, Pharmacological Characterization and Amino Acid Sequence by Mass Spectrometry

A monomeric basic PLA2 (PhTX-II) of 14149.08 Da molecular weight was purified to homogeneity from Porthidium hyoprora venom. Amino acid sequence by in tandem mass spectrometry revealed that PhTX-II belongs to Asp49 PLA2 enzyme class and displays conserved domains as the catalytic network, Ca2+-bind...

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Bibliographic Details
Main Authors: Salomón Huancahuire-Vega, Luis Alberto Ponce-Soto, Sergio Marangoni
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/6/11/3077