Novel Calcium Phosphate Cement with Metformin-Loaded Chitosan for Odontogenic Differentiation of Human Dental Pulp Cells

Metformin is an old and widely accepted first-line drug for treating type 2 diabetes. Our previous studies demonstrate that metformin can stimulate the osteo/odontogenic differentiation of human-induced pluripotent stem cell-derived mesenchymal stem cells and human dental pulp cells (DPCs). Due to t...

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Bibliographic Details
Main Authors: Wei Qin, Jia-Yao Chen, Jia Guo, Tao Ma, Michael D. Weir, Dong Guo, Yan Shu, Zheng-Mei Lin, Abraham Schneider, Hockin H. K. Xu
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2018/7173481