Verification of neuroprotective effects of alpha-lipoic acid on chronic neuropathic pain in a chronic constriction injury rat model

Verification of neuroprotective effects of alpha-lipoic acid on chronic neuropathic pain in a chronic constriction injury rat model

Treatment of neuropathic pain is far from satisfactory. This study sought evidence of a neuroprotective effect of alpha-lipoic acid (ALA) to treat neuropathic pain in a chronic constriction injury (CCI) rat model. A total of 48 rats were randomly divided into sham, CCI, or CCI + ALA groups. Mechanic...

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Bibliographic Details
Main Authors: Wang Junhao, Lou Zhaohui, Xi Haiyang, Li Zhi, Li Lepeng, Li Zhenzhen, Zhang Kai, Asakawa Tetsuya
Format: Article
Language:English
Published: De Gruyter 2021-03-01
Series:Open Life Sciences
Subjects:
neuropathic pain
peripheral nerve injury
alpha-lipoic acid
satellite glial cells
dorsal root ganglia
Online Access:https://doi.org/10.1515/biol-2021-0026

Internet

https://doi.org/10.1515/biol-2021-0026

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