New combinations and immunotherapies for melanoma: latest evidence and clinical utility

Until recently there was no effective systemic therapy for metastatic melanoma. Increased understanding of tumor biology and immune regulation has led to the development of drugs targeting the mitogen-activated protein kinase (MAPK) pathway (BRAF inhibitors and MEK inhibitors) and T-cell regulation...

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Bibliographic Details
Main Authors: Alexander M. Menzies, Georgina V. Long
Format: Article
Language:English
Published: SAGE Publishing 2013-09-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758834013499637