Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents

Targeting small molecules to appropriate subcellular compartments is a way to increase their selectivity and effectiveness while minimizing side effects. This can be accomplished either by stably incorporating specific “homing” properties into the structure of the active principle, or by attaching t...

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Bibliographic Details
Main Authors: Andrea Mattarei, Matteo Romio, Antonella Managò, Mario Zoratti, Cristina Paradisi, Ildikò Szabò, Luigi Leanza, Lucia Biasutto
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2018.00122/full