Pathophysiological Significance of Dermatan Sulfate Proteoglycans Revealed by Human Genetic Disorders

The indispensable roles of dermatan sulfate-proteoglycans (DS-PGs) have been demonstrated in various biological events including construction of the extracellular matrix and cell signaling through interactions with collagen and transforming growth factor-β, respectively. Defects in the core proteins...

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Bibliographic Details
Main Authors: Shuji Mizumoto, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/10/2/34