The Relevancy of Data Regarding the Metabolism of Iron to Our Understanding of Deregulated Mechanisms in ALS; Hypotheses and Pitfalls

The Relevancy of Data Regarding the Metabolism of Iron to Our Understanding of Deregulated Mechanisms in ALS; Hypotheses and Pitfalls

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the loss of motor neurons. Its etiology remains unknown, but several pathophysiological mechanisms are beginning to explain motor neuronal death, as well as oxidative stress. Iron accumulation has been observed in both spor...

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Bibliographic Details
Main Authors: Camille Petillon, Rudolf Hergesheimer, Hervé Puy, Philippe Corcia, Patrick Vourc’h, Christian Andres, Zoubida Karim, Hélène Blasco
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Neuroscience
Subjects:
iron metabolism
amyotrophic lateral sclerosis
ferritin
biomarkers
ALS
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.01031/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.01031/full

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