Impaired glucose metabolism and altered gut microbiome despite calorie restriction of ob/ob mice

Impaired glucose metabolism and altered gut microbiome despite calorie restriction of ob/ob mice

Abstract Background Growing evidence supports the role of gut microbiota in obesity and its related disorders including type 2 diabetes. Ob/ob mice, which are hyperphagic due to leptin deficiency, are commonly used models of obesity and were instrumental in suggesting links between gut microbiota an...

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Bibliographic Details
Main Authors: Alireza Kashani, Asker Daniel Brejnrod, Chunyu Jin, Timo Kern, Andreas Nygaard Madsen, Louise Aas Holm, Georg K. Gerber, Jens-Christian Holm, Torben Hansen, Birgitte Holst, Manimozhiyan Arumugam
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Animal Microbiome
Subjects:
Calorie restriction
Leptin deficiency
Leptin-deficient mice
Mouse gut microbiota
Obesity
Ob/Ob mice
Online Access:http://link.springer.com/article/10.1186/s42523-019-0007-1

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http://link.springer.com/article/10.1186/s42523-019-0007-1

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