Galleria mellonella infection model demonstrates high lethality of ST69 and ST127 uropathogenic E. coli.

Galleria mellonella larvae are an alternative in vivo model for investigating bacterial pathogenicity. Here, we examined the pathogenicity of 71 isolates from five leading uropathogenic E. coli (UPEC) lineages using G. mellonella larvae. Larvae were challenged with a range of inoculum doses to deter...

Full description

Bibliographic Details
Main Authors: Majed F Alghoribi, Tarek M Gibreel, Andrew R Dodgson, Scott A Beatson, Mathew Upton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4111486?pdf=render