Distinct Spontaneous Brain Activity Patterns in Different Biologically-Defined Alzheimer’s Disease Cognitive Stage: A Preliminary Study

Distinct Spontaneous Brain Activity Patterns in Different Biologically-Defined Alzheimer’s Disease Cognitive Stage: A Preliminary Study

Background: The National Institute on Aging-Alzheimer’s Association (NIA-AA) has proposed a biological definition of Alzheimer’s disease (AD): individuals with both abnormal amyloid and tau biomarkers (A+T+) would be defined as AD. It remains unclear why different cognitive status is present in subj...

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Bibliographic Details
Main Authors: Qingze Zeng, Xiao Luo, Kaicheng Li, Shuyue Wang, Ruiting Zhang, Hui Hong, Peiyu Huang, Yeerfan Jiaerken, Xiaojun Xu, Jingjing Xu, Chao Wang, Jiong Zhou, Minming Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
A/T/N system
spontaneous neuronal activity
functional magnetic resonance imaging
fractional amplitude of low-frequency fluctuation
cerebrospinal fluid
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00350/full

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https://www.frontiersin.org/article/10.3389/fnagi.2019.00350/full

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