Monocyte Dysfunction Detected by the Designed Ankyrin Repeat Protein F7 Predicts Mortality in Patients Receiving Veno-Arterial Extracorporeal Membrane Oxygenation

Monocyte Dysfunction Detected by the Designed Ankyrin Repeat Protein F7 Predicts Mortality in Patients Receiving Veno-Arterial Extracorporeal Membrane Oxygenation

Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is used for critically ill patients requiring hemodynamic support but has been shown to induce an inflammatory response syndrome potentially leading to severe complications and poor outcome. Monocytes are comprised of different...

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Bibliographic Details
Main Authors: Patrick M. Siegel, Lukas Orlean, István Bojti, Klaus Kaier, Thilo Witsch, Jennifer S. Esser, Georg Trummer, Martin Moser, Karlheinz Peter, Christoph Bode, Philipp Diehl
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
extracorporeal membrane oxygenation
monocyte
Mac-1
inflammation
DARPin®
activation
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.689218/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.689218/full

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