Role of Herpes Simplex Envelope Glycoprotein B and Toll-Like Receptor 2 in Ocular Inflammation: An Ex Vivo Organotypic Rabbit Corneal Model

Role of Herpes Simplex Envelope Glycoprotein B and Toll-Like Receptor 2 in Ocular Inflammation: An Ex Vivo Organotypic Rabbit Corneal Model

It has been recently reported, using in vitro studies, that the herpes simplex virus 1 (HSV-1) encoded envelope glycoprotein B (gB1) interacts with cell surface toll-like receptor 2 (TLR2) and induces the secretion of interleukin-8 (IL8), a representative marker of inflammatory cytokine activation....

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Bibliographic Details
Main Authors: Andreana Marino, Simona Pergolizzi, Francesco Cimino, Eugenia Rita Lauriano, Antonio Speciale, Valeria D’Angelo, Mariaconcetta Sicurella, Rafaela Argnani, Roberto Manservigi, Peggy Marconi
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Viruses
Subjects:
HSV-1 gB
TLR2
ex vivo corneal model
mydriasis
Online Access:https://www.mdpi.com/1999-4915/11/9/819

Internet

https://www.mdpi.com/1999-4915/11/9/819

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