Rhinovirus Infection Drives Complex Host Airway Molecular Responses in Children With Cystic Fibrosis

Rhinovirus Infection Drives Complex Host Airway Molecular Responses in Children With Cystic Fibrosis

Early-life viral infections are responsible for pulmonary exacerbations that can contribute to disease progression in young children with cystic fibrosis (CF). The most common respiratory viruses detected in the CF airway are human rhinoviruses (RV), and augmented airway inflammation in CF has been...

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Bibliographic Details
Main Authors: Kak-Ming Ling, Luke W. Garratt, Erin E. Gill, Amy H. Y. Lee, Patricia Agudelo-Romero, Erika N. Sutanto, Thomas Iosifidis, Tim Rosenow, Stuart E. Turvey, Timo Lassmann, Robert E. W. Hancock, Anthony Kicic, Stephen M. Stick
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
cystic fibrosis
RV
airway epithelial cells
transcriptomic
innate immune response
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01327/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01327/full

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