Rapid generation of sub-type, region-specific neurons and neural networks from human pluripotent stem cell-derived neurospheres

Stem cell-based neuronal differentiation has provided a unique opportunity for disease modeling and regenerative medicine. Neurospheres are the most commonly used neuroprogenitors for neuronal differentiation, but they often clump in culture, which has always represented a challenge for neurodiffere...

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Bibliographic Details
Main Authors: Aynun N. Begum, Caleigh Guoynes, Jane Cho, Jijun Hao, Kabirullah Lutfy, Yiling Hong
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Stem Cell Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S187350611500149X