The hippo signaling pathway: implications for heart regeneration and disease
Abstract Control of cell number and organ size is critical for appropriate development and tissue homeostasis. Studies in both Drosophila and mammals have established the Hippo signaling pathway as an important modulator of organ size and tumorigenesis. Upon activation, this kinase cascade modulates...
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Format: | Article |
Language: | English |
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Wiley
2014-12-01
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Series: | Clinical and Translational Medicine |
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Online Access: | https://doi.org/10.1186/s40169-014-0027-0 |