Overcoming multidrug resistance by intracellular drug release and inhibiting p-glycoprotein efflux in breast cancer
Doxorubicin (DOX) is limited to use in clinical practice because of poor targeting, serious side effects and multidrug resistance (MDR). Vitamin E and its derivatives are currently considered as hydrophobic material that can reverse tumor MDR by suppressing the action of p-glycoprotein (p-gp). There...
Main Authors: | Jing Mao, Lipeng Qiu, Lu Ge, Juan Zhou, Qian Ji, Yang Yang, Miaomiao Long, Danhui Wang, Liping Teng, Jinghua Chen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-02-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332220313019 |
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