Association between rare variants in specific functional pathways and human neural tube defects multiple subphenotypes

Association between rare variants in specific functional pathways and human neural tube defects multiple subphenotypes

Abstract Background Neural tube defects (NTDs) are failure of neural tube closure, which includes multiple central nervous system phenotypes. More than 300 mouse mutant strains exhibits NTDs phenotypes and give us some clues to establish association between biological functions and subphenotypes. Ho...

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Bibliographic Details
Main Authors: Jizhen Zou, Fang Wang, Xueyan Yang, Hongyan Wang, Lee Niswander, Ting Zhang, Huili Li
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Neural Development
Subjects:
Neural tube defect
Neural tube closure
Mutation
Spina bifida
Human
Online Access:http://link.springer.com/article/10.1186/s13064-020-00145-7

Internet

http://link.springer.com/article/10.1186/s13064-020-00145-7

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