Anti-IFN-γ therapy alleviates acute lung injury induced by severe influenza A (H1N1) pdm09 infection in mice

Background/purpose: Severe infection with influenza A (H1N1)pdm09 virus is characterized by acute lung injury. The limited efficacy of anti-viral drugs indicates an urgent need for additional therapies. We have previously reported that neutralization of gamma interferon (IFN-γ) could significantly r...

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Bibliographic Details
Main Authors: Bo Liu, LinLin Bao, Li Wang, Fengdi Li, Mingjie Wen, Hui Li, Wei Deng, Xulong Zhang, Bin Cao
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Journal of Microbiology, Immunology and Infection
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118218304389