Anticonvulsant and proconvulsant roles of nitric oxide in experimental epilepsy models

Anticonvulsant and proconvulsant roles of nitric oxide in experimental epilepsy models

The effect of acute (120 mg/kg) and chronic (25 mg/kg, twice a day, for 4 days) intraperitonial injection of the nitric oxide (NO) synthase (NOS) inhibitor NG-nitro-L-arginine (L-NOARG) was evaluated on seizure induction by drugs such as pilocarpine and pentylenetetrazole (PTZ) and by sound stimulat...

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Bibliographic Details
Main Authors: Del-Bel E.A., Oliveira P.R., Oliveira J.A.C., Mishra P.K., Jobe P.C., Garcia-Cairasco N.
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1997-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
experimental epilepsy
seizures
forebrain
brainstem
pilocarpine
pentylenetetrazol
audiogenic seizures
genetically epilepsy-prone rats
GEPR
nitric oxide
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800010

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800010

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