Structural Basis for the Inhibition of the Autophosphorylation Activity of HK853 by Luteolin

The two-component system (TCS) is a significant signal transduction system for bacteria to adapt to complicated and variable environments, and thus has recently been regarded as a novel target for developing antibacterial agents. The natural product luteolin (Lut) can inhibit the autophosphorylation...

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Bibliographic Details
Main Authors: Yuan Zhou, Liqun Huang, Shixia Ji, Shi Hou, Liang Luo, Conggang Li, Maili Liu, Yixiang Liu, Ling Jiang
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
ATP
NMR
Online Access:http://www.mdpi.com/1420-3049/24/5/933