Clearance Concepts: Fundamentals and Application to Pharmacokinetic Behavior of Drugs
Clearance concepts were introduced into the pharmacokinetics discipline in the 1970s and since then have played a major role in characterization of the pharmacokinetic behavior of drugs. These concepts are based on the relationship between organ extraction ratio or clearance and physiologic paramet...
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Format: | Article |
Language: | English |
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Canadian Society for Pharmaceutical Sciences
2018-05-01
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Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/29896 |