Laser capture microscopy coupled with Smart-seq2 for precise spatial transcriptomic profiling
Laser capture microscopy (LCM) coupled with global transcriptome profiling requires relatively large numbers of cells. Here, the authors show that LCM coupled with full-length mRNA-sequencing (LCM-seq) can sequence single cells, and that LCM-seq can provide biological insight on highly similar neuro...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-07-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms12139 |