Effects of simvastatin on white matter integrity in healthy middle‐aged adults

Abstract Background The brain is the most cholesterol‐rich organ and myelin contains 70% of total brain cholesterol. Statins are potent cholesterol‐lowing medications used by millions of adults for prevention of vascular disease, yet the effect of statins on cholesterol‐rich brain white matter (WM)...

Full description

Bibliographic Details
Main Authors: Nicholas M. Vogt, Jack F. V. Hunt, Yue Ma, Carol A. Van Hulle, Nagesh Adluru, Richard J. Chappell, Karen K. Lazar, Laura E Jacobson, Benjamin P. Austin, Sanjay Asthana, Sterling C. Johnson, Barbara B. Bendlin, Cynthia M. Carlsson
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51421