MicroRNA-21-Enriched Exosomes as Epigenetic Regulators in Melanomagenesis and Melanoma Progression: The Impact of Western Lifestyle Factors

MicroRNA-21-Enriched Exosomes as Epigenetic Regulators in Melanomagenesis and Melanoma Progression: The Impact of Western Lifestyle Factors

DNA mutation-induced activation of RAS-BRAF-MEK-ERK signaling associated with intermittent or chronic ultraviolet (UV) irradiation cannot exclusively explain the excessive increase of malignant melanoma (MM) incidence since the 1950s. Malignant conversion of a melanocyte to an MM cell and metastatic...

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Bibliographic Details
Main Authors: Bodo C. Melnik, Swen Malte John, Pedro Carrera-Bastos, Gerd Schmitz
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
environment
epigenetics
exosome
melanoma
metabolic syndrome
microRNA-21
Online Access:https://www.mdpi.com/2072-6694/12/8/2111

Internet

https://www.mdpi.com/2072-6694/12/8/2111

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