Ameliorative Effect of Curcumin-Encapsulated Hyaluronic Acid–PLA Nanoparticles on Thioacetamide-Induced Murine Hepatic Fibrosis

Ameliorative Effect of Curcumin-Encapsulated Hyaluronic Acid–PLA Nanoparticles on Thioacetamide-Induced Murine Hepatic Fibrosis

In this study, we developed curcumin-encapsulated hyaluronic acid–polylactide nanoparticles (CEHPNPs) to be used for liver fibrosis amelioration. CD44, the hyaluronic acid (HA) receptor, is upregulated on the surface of cancer cells and on activated hepatic stellate cells (aHSCs) rather than normal...

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Bibliographic Details
Main Authors: Yu-Nong Chen, Shih-Lan Hsu, Ming-Yuan Liao, Yi-Ting Liu, Chien-Hung Lai, Ji-Feng Chen, Mai-Huong Thi Nguyen, Yung-Hsiang Su, Shang-Ting Chen, Li-Chen Wu
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Environmental Research and Public Health
Subjects:
hyaluronic acid
curcumin
nanoparticle
hepatic stellate cells
liver fibrosis
Online Access:http://www.mdpi.com/1660-4601/14/1/11

Internet

http://www.mdpi.com/1660-4601/14/1/11

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