Mechanical Abnormalities of the Airway Wall in Adult Mice After Intrauterine Growth Restriction

Mechanical Abnormalities of the Airway Wall in Adult Mice After Intrauterine Growth Restriction

Developmental abnormalities of airways may impact susceptibility to asthma in later life. We used a maternal hypoxia-induced mouse model of intrauterine growth restriction (IUGR) to examine changes in mechanical properties of the airway wall. Pregnant BALB/c mice were housed under hypoxic conditions...

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Bibliographic Details
Main Authors: Peter B. Noble, Darshinee Kowlessur, Alexander N. Larcombe, Graham M. Donovan, Kimberley C. W. Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Physiology
Subjects:
intrauterine growth restriction
low birth weight
animal models
asthma
respiratory structure and function
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01073/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01073/full

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