A Comparative View on Human Somatic Cell Sources for iPSC Generation

The breakthrough of reprogramming human somatic cells was achieved in 2006 by the work of Yamanaka and Takahashi. From this point, fibroblasts are the most commonly used primary somatic cell type for the generation of induced pluripotent stem cells (iPSCs). Various characteristics of fibroblasts sup...

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Bibliographic Details
Main Authors: Stefanie Raab, Moritz Klingenstein, Stefan Liebau, Leonhard Linta
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2014/768391