Identification of a Bipotent Epithelial Progenitor Population in the Adult Thymus

Thymic epithelial cells (TECs) are critically required for T cell development, but the cellular mechanisms that maintain adult TECs are poorly understood. Here, we show that a previously unidentified subpopulation, EpCam+UEA1−Ly-51+PLET1+MHC class IIhi, which comprises <0.5% of adult TECs, contai...

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Bibliographic Details
Main Authors: Svetlana Ulyanchenko, Kathy E. O’Neill, Tanya Medley, Alison M. Farley, Harsh J. Vaidya, Alistair M. Cook, Natalie F. Blair, C. Clare Blackburn
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716302157