Direct Inhibition of IRF-Dependent Transcriptional Regulatory Mechanisms Associated With Disease

Direct Inhibition of IRF-Dependent Transcriptional Regulatory Mechanisms Associated With Disease

Interferon regulatory factors (IRFs) are a family of homologous proteins that regulate the transcription of interferons (IFNs) and IFN-induced gene expression. As such they are important modulating proteins in the Toll-like receptor (TLR) and IFN signaling pathways, which are vital elements of the i...

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Bibliographic Details
Main Authors: Aleksandra Antonczyk, Bart Krist, Malgorzata Sajek, Agata Michalska, Anna Piaszyk-Borychowska, Martyna Plens-Galaska, Joanna Wesoly, Hans A. R. Bluyssen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
IRF
interferon
TLR
transcriptional regulation
inflammation
inhibition
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01176/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01176/full

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