Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics

Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics

Nanoparticle applications are limited by insufficient understanding of physiochemical properties on in vivo disposition. Here, the authors explore the influence of size, surface chemistry and administration on the biodisposition of mesoporous silica nanoparticles using image-based pharmacokinetics.

Bibliographic Details
Main Authors: Prashant Dogra, Natalie L. Adolphi, Zhihui Wang, Yu-Shen Lin, Kimberly S. Butler, Paul N. Durfee, Jonas G. Croissant, Achraf Noureddine, Eric N. Coker, Elaine L. Bearer, Vittorio Cristini, C. Jeffrey Brinker
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06730-z

Internet

https://doi.org/10.1038/s41467-018-06730-z

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