To investigate the necessity of STRA6 upregulation in T cells during T cell immune responses.

To investigate the necessity of STRA6 upregulation in T cells during T cell immune responses.

Our earlier study revealed that STRA6 (stimulated by retinoic acid gene 6) was up-regulated within 3 h of TCR stimulation. STRA6 is the high-affinity receptor for plasma retinol-binding protein (RBP) and mediates cellular vitamin A uptake. We generated STRA6 knockout (KO) mice to assess whether such...

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Bibliographic Details
Main Authors: Rafik Terra, Xuehai Wang, Yan Hu, Tania Charpentier, Alain Lamarre, Ming Zhong, Hui Sun, Jianning Mao, Shijie Qi, Hongyu Luo, Jiangping Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3876989?pdf=render

Internet

http://europepmc.org/articles/PMC3876989?pdf=render

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