Characterization of T-Cell Responses to SMX and SMX-NO in Co-Trimoxazole Hypersensitivity Patients Expressing HLA-B*13:01

Characterization of T-Cell Responses to SMX and SMX-NO in Co-Trimoxazole Hypersensitivity Patients Expressing HLA-B*13:01

HLA-B*13:01-positive patients in Thailand can develop frequent co-trimoxazole hypersensitivity reactions. This study aimed to characterize drug-specific T cells from three co-trimoxazole hypersensitive patients presenting with either Stevens-Johnson syndrome or drug reaction with eosinophilia and sy...

Full description

Bibliographic Details
Main Authors: Jirawat Pratoomwun, Paul Thomson, Kanoot Jaruthamsophon, Rawiporn Tiyasirichokchai, Pimonpan Jinda, Ticha Rerkpattanapipat, Wichittra Tassaneeyakul, Nontaya Nakkam, Pawinee Rerknimitr, Jettanong Klaewsongkram, Yuttana Srinoulprasert, Munir Pirmohamed, Dean J. Naisbitt, Chonlaphat Sukasem
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
co-trimoxazole
drug hypersensitivity
human leukocyte antigen
sulfamethoxazole
T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.658593/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.658593/full

Similar Items