Carbamazepine solubility enhancement in tandem with swellable polymer osmotic pump tablet: A promising approach for extended delivery of poorly water-soluble drugs

Carbamazepine solubility enhancement in tandem with swellable polymer osmotic pump tablet: A promising approach for extended delivery of poorly water-soluble drugs

Elementary osmotic pump (EOP) is a unique extended release (ER) drug delivery system based on the principle of osmosis. It has the ability to minimize the amount of the drug, accumulation and fluctuation in drug level during chronic uses. Carbamazepine (CBZ), a poorly water-soluble antiepileptic dru...

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Bibliographic Details
Main Authors: Hadjira Rabti, Jumah Masoud Mohammed Salmani, Eltayeb Sulimen Elamin, Narimane Lammari, Jie Zhang, Qineng Ping
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Elementary osmotic pump
Carbamazepine
Solubility enhancement
Taguchi orthogonal design
Zero order
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087614000191

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http://www.sciencedirect.com/science/article/pii/S1818087614000191

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