Altered composition of bone as triggered by irradiation facilitates the rapid erosion of the matrix by both cellular and physicochemical processes.

Altered composition of bone as triggered by irradiation facilitates the rapid erosion of the matrix by both cellular and physicochemical processes.

Radiation rapidly undermines trabecular architecture, a destructive process which proceeds despite a devastated cell population. In addition to the 'biologically orchestrated' resorption of the matrix by osteoclasts, physicochemical processes enabled by a damaged matrix may contribute to t...

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Bibliographic Details
Main Authors: Danielle E Green, Benjamin J Adler, Meilin Ete Chan, James J Lennon, Alvin S Acerbo, Lisa M Miller, Clinton T Rubin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3669258?pdf=render

Internet

http://europepmc.org/articles/PMC3669258?pdf=render

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