Cold-Pressed <i>Nigella Sativa</i> Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied with Conversion of White to Beige Fat in Mice

Cold-Pressed <i>Nigella Sativa</i> Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied with Conversion of White to Beige Fat in Mice

Excessive lipid accumulation in white adipose tissue (WAT) results in adipocyte hypertrophy and chronic low-grade inflammation, which is the major cause of obesity-associated insulin resistance and consequent metabolic disease. The development of beige adipocytes in WAT (browning of WAT) increases e...

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Bibliographic Details
Main Authors: Hsin Hsueh Shen, Stephen J. Peterson, Lars Bellner, Abu Choudhary, Lior Levy, Leah Gancz, Ariel Sasson, Joseph Trainer, Rita Rezzani, Abraham Resnick, David E. Stec, Nader G. Abraham
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Antioxidants
Subjects:
obesity
inflammation
thymoquinone
omega 3
beige adipocyte
insulin resistance
Online Access:https://www.mdpi.com/2076-3921/9/6/489

Internet

https://www.mdpi.com/2076-3921/9/6/489

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