Mass Cytometry Discovers Two Discrete Subsets of CD39−Treg Which Discriminate MGUS From Multiple Myeloma

Mass Cytometry Discovers Two Discrete Subsets of CD39−Treg Which Discriminate MGUS From Multiple Myeloma

Multiple Myeloma (MM) is preceded by the clinically stable condition monoclonal gammopathy of undetermined significance (MGUS). Critical immune events that discriminate MGUS from newly diagnosed MM (ND)MM patients remain unknown, but may involve changes in the regulatory T cell (Treg) compartment th...

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Bibliographic Details
Main Authors: Felix Marsh-Wakefield, Annabel Kruzins, Helen M. McGuire, Shihong Yang, Christian Bryant, Barbara Fazekas de St. Groth, Najah Nassif, Scott N. Byrne, John Gibson, Christina Brown, Stephen Larsen, Derek McCulloch, Richard Boyle, Georgina Clark, Douglas Joshua, Phoebe Joy Ho, Slavica Vuckovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
MGUS
multiple myeloma
mass cytometry
FlowSom
Treg
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01596/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01596/full

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