Updated protocol of the SANO trial: a stepped-wedge cluster randomised trial comparing surgery with active surveillance after neoadjuvant chemoradiotherapy for oesophageal cancer

Updated protocol of the SANO trial: a stepped-wedge cluster randomised trial comparing surgery with active surveillance after neoadjuvant chemoradiotherapy for oesophageal cancer

Abstract Background The Surgery As Needed for Oesophageal cancer (SANO) trial compares active surveillance with standard oesophagectomy for patients with a clinically complete response (cCR) to neoadjuvant chemoradiotherapy. The last patient with a clinically complete response is expected to be incl...

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Bibliographic Details
Main Authors: Ben M. Eyck, Berend J. van der Wilk, Bo Jan Noordman, Bas P. L. Wijnhoven, Sjoerd M. Lagarde, Henk H. Hartgrink, Peter Paul L. O. Coene, Jan Willem T. Dekker, Michail Doukas, Ate van der Gaast, Joos Heisterkamp, Ewout A. Kouwenhoven, Grard A. P. Nieuwenhuijzen, Jean-Pierre E. N. Pierie, Camiel Rosman, Johanna W. van Sandick, Maurice J. C. van der Sangen, Meindert N. Sosef, Edwin S. van der Zaag, Manon C. W. Spaander, Roelf Valkema, Hester F. Lingsma, Ewout W. Steyerberg, J. Jan B. van Lanschot, on behalf of the SANO-study group
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Trials
Subjects:
Oesophageal cancer
Neoadjuvant chemoradiotherapy
Active surveillance
Standard oesophagectomy
Online Access:https://doi.org/10.1186/s13063-021-05274-w

Internet

https://doi.org/10.1186/s13063-021-05274-w

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