SB203580 Modulates p38 MAPK Signaling and Dengue Virus-Induced Liver Injury by Reducing MAPKAPK2, HSP27, and ATF2 Phosphorylation.

Dengue virus (DENV) infection causes organ injuries, and the liver is one of the most important sites of DENV infection, where viral replication generates a high viral load. The molecular mechanism of DENV-induced liver injury is still under investigation. The mitogen activated protein kinases (MAPK...

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Main Authors: Gopinathan Pillai Sreekanth, Aporn Chuncharunee, Aunchalee Sirimontaporn, Jutatip Panaampon, Sansanee Noisakran, Pa-Thai Yenchitsomanus, Thawornchai Limjindaporn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4764010?pdf=render