Human Cell-Based in vitro Phenotypic Profiling for Drug Safety-Related Attrition

Ensuring the safety of new drugs is critically important to regulators, pharmaceutical researchers and patients alike. Even so, unexpected toxicities still account for 20–30% of clinical trial failures, in part due to the persistence of animal testing as the primary approach for de-risking new drugs...

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Bibliographic Details
Main Author: Ellen L. Berg
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Big Data
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fdata.2019.00047/full