The role of metabolism in bacterial persistence

The role of metabolism in bacterial persistence

Bacterial persisters are phenotypic variants with extraordinary tolerances toward antibiotics. Persister survival has been attributed to inhibition of essential cell functions during antibiotic stress, followed by reversal of the process and resumption of growth upon removal of the antibiotic. Metab...

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Bibliographic Details
Main Authors: Stephanie M. Amato, Christopher H. Fazen, Theresa C. Henry, Wendy W. K. Mok, Mehmet A. Orman, Elizabeth L. Sandvik, Katherine G. Volzing, Mark P. Brynildsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Microbiology
Subjects:
Metabolism
antibiotic tolerance
bacterial persistence
ppGpp
nutrient environment
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00070/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00070/full

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