Detection of <i>KRAS</i> G12/G13 Mutations in Cell Free-DNA by Droplet Digital PCR, Offers Prognostic Information for Patients with Advanced Non-Small Cell Lung Cancer

Detection of <i>KRAS</i> G12/G13 Mutations in Cell Free-DNA by Droplet Digital PCR, Offers Prognostic Information for Patients with Advanced Non-Small Cell Lung Cancer

<i>KRAS</i> mutations are found in approximately one third of non-small cell lung cancer (NSCLC) patients. In this study, we aim to investigate whether <i>KRAS</i> G12/G13 mutant allele fraction (MAF) in cell-free DNA (cfDNA) can provide meaningful prognostic information in N...

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Bibliographic Details
Main Authors: Kleita Michaelidou, Chara Koutoulaki, Konstantinos Mavridis, Eleftherios Vorrias, Maria A. Papadaki, Anastasios V. Koutsopoulos, Dimitrios Mavroudis, Sofia Agelaki
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
ctDNA
NSCLC
ddPCR
liquid biopsy
prognostic biomarker
molecular testing
Online Access:https://www.mdpi.com/2073-4409/9/11/2514

Internet

https://www.mdpi.com/2073-4409/9/11/2514

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