Activity dependent protein degradation is critical for the formation and stability of fear memory in the amygdala.

Protein degradation through the ubiquitin-proteasome system [UPS] plays a critical role in some forms of synaptic plasticity. However, its role in memory formation in the amygdala, a site critical for the formation of fear memories, currently remains unknown. Here we provide the first evidence that...

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Bibliographic Details
Main Authors: Timothy J Jarome, Craig T Werner, Janine L Kwapis, Fred J Helmstetter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21961035/pdf/?tool=EBI