Activated neutrophils polarize protumorigenic interleukin‐17A‐producing T helper subsets through TNF‐α‐B7‐H2‐dependent pathway in human gastric cancer

Activated neutrophils polarize protumorigenic interleukin‐17A‐producing T helper subsets through TNF‐α‐B7‐H2‐dependent pathway in human gastric cancer

Abstract Rationale Neutrophils constitute massive cellular constituents in inflammatory human gastric cancer (GC) tissues, but their roles in pathogenesis of inflammatory T helper (Th) subsets are still unknown. Methods Flow cytometry analysis and immunohistochemistry were used to analyze the respon...

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Bibliographic Details
Main Authors: Zhi‐guo Shan, Jun Chen, Jin‐shan Liu, Jin‐yu Zhang, Ting‐ting Wang, Yong‐sheng Teng, Fang‐yuan Mao, Ping Cheng, Quan‐ming Zou, Wei‐ying Zhou, Liu‐sheng Peng, Yong‐liang Zhao, Yuan Zhuang
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Clinical and Translational Medicine
Subjects:
B7‐H2
gastric cancer
IL‐17A
neutrophils
Online Access:https://doi.org/10.1002/ctm2.484

Internet

https://doi.org/10.1002/ctm2.484

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