Preclinical assessment of dual CYP26[A1/B1] inhibitor, DX308, as an improved treatment for keratinization disorders

Abstract Background Retinoid‐based therapies are commonly used in the treatment of disorders of keratinization and other skin disorders but can result in non‐specific effects and adverse reactions. Use of retinoic acid metabolism blocking agents (RAMBAs) such as DX308 may address these shortcomings....

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Bibliographic Details
Main Authors: J.G.S. Veit, Y. Poumay, D. Mendes, J. Kreitinger, L. Walker, A. Paquet, C. Menigot, F. Zolezzi, A.S. Paller, P. Diaz
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Skin Health and Disease
Online Access:https://doi.org/10.1002/ski2.22