Interferon-gamma release assay performance in northeastern Brazil: influence of the IFNG + 874 A>T polymorphism

Interferon-gamma release assay performance in northeastern Brazil: influence of the IFNG + 874 A>T polymorphism

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ABSTRACT Introduction Latent tuberculosis infection diagnosis based on the release of interferon-gamma in cultures of peripheral blood cells stimulated with Mycobacterium tuberculosis antigens has replaced the tuberculin skin test in many countries with low tuberculosis prevalence. The IFN-γ produc...

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Bibliographic Details
Main Authors: Valdirene Leão Carneiro, Maria Teresita Bendicho, Rosalina Guedes Santos, Marilda Casela, Eduardo M. Netto, Scarlet Torres Moraes Mota, Iza Cristina Araújo Pina, Roberto Meyer Nascimento, Songeli Menezes Freire, Theolis Barbosa
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
Tuberculosis infection
Genetic variation
Sensitivity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000300202&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000300202&lng=en&tlng=en

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