TGF-β Signaling May Play a Role in the Development of Goblet Cell Hyperplasia in a Mouse Model of Allergic Rhinitis

TGF-β Signaling May Play a Role in the Development of Goblet Cell Hyperplasia in a Mouse Model of Allergic Rhinitis

ABSTRACT: Background: Transforming growth factor-p (TGF-β) levels are elevated in the nasal mucosa in allergic rhinitis. However, because TGF-β is secreted extracellulary in latent complexes, it remains unclear whether the local TGF-β expression actually drives active signaling and affects the path...

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Main Authors: Yuhui Ouyang, Masanori Miyata, Kyosuke Hatsushika, Yuko Ohnuma, Ryohei Katoh, Hideoki Ogawa, Ko Okumura, Keisuke Masuyama, Atsuhito Nakao
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Allergology International
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015306419

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http://www.sciencedirect.com/science/article/pii/S1323893015306419

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