HIV-infected cells are frequently clonally expanded after prolonged antiretroviral therapy: implications for HIV persistence

HIV infection is controlled but not eradicated by combination antiretroviral therapy (cART), and persistence during therapy represents a substantial barrier to strategies to eradicate infection. The nature of persistence is uncertain, and a number of mechanisms have been proposed to explain HIV pers...

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Bibliographic Details
Main Author: Frank Maldarelli
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Journal of Virus Eradication
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664020309304