Limited Cross-Protection against Infectious Bronchitis Provided by Recombinant Infectious Bronchitis Viruses Expressing Heterologous Spike Glycoproteins

Limited Cross-Protection against Infectious Bronchitis Provided by Recombinant Infectious Bronchitis Viruses Expressing Heterologous Spike Glycoproteins

<i>Gammacoronavirus</i> infectious bronchitis virus (IBV) causes an economically important respiratory disease of poultry. Protective immunity is associated with the major structural protein, spike (S) glycoprotein, which induces neutralising antibodies and defines the serotype. Cross-pr...

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Bibliographic Details
Main Authors: Sarah Keep, Samantha Sives, Phoebe Stevenson-Leggett, Paul Britton, Lonneke Vervelde, Erica Bickerton
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Vaccines
Subjects:
infectious bronchitis virus
coronavirus
reverse genetics
recombinant vaccine
spike glycoprotein
heterologous challenge
Online Access:https://www.mdpi.com/2076-393X/8/2/330

Internet

https://www.mdpi.com/2076-393X/8/2/330

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