Elevated plasma corticosterone level and depressive behavior in experimental temporal lobe epilepsy

Elevated plasma corticosterone level and depressive behavior in experimental temporal lobe epilepsy

Depression is frequently reported in epilepsy patients; however, mechanisms of co-morbidity between epilepsy and depression are poorly understood. An important mechanism of depression is disinhibition within the hypothalamo–pituitary–adrenocortical (HPA) axis. We examined the functional state of the...

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Bibliographic Details
Main Authors: Andrey M. Mazarati, Don Shin, Young Se Kwon, Anatol Bragin, Eduardo Pineda, Delia Tio, Anna N. Taylor, Raman Sankar
Format: Article
Language:English
Published: Elsevier 2009-06-01
Series:Neurobiology of Disease
Subjects:
Epilepsy
Depression
Co-morbidity
Hypothalamo–pituitary–adrenocortical axis
Chronic stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109000540

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http://www.sciencedirect.com/science/article/pii/S0969996109000540

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